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Expert Identify Foods That Increase Hypertension Medication’s Effectiveness

Published

5 months ago

January 8, 2026

Hypertension remains one of the leading causes of premature death worldwide, contributing significantly to heart disease, stroke, and kidney failure. Despite the availability of effective antihypertensive drugs, long-term control of high blood pressure is often challenging because of drug resistance, side effects, and poor adherence.

This has fueled growing scientific interest in complementary strategies that can enhance drug efficacy while minimising toxicity. One promising approach is the combination of conventional antihypertensive medications with herbs and spices in many kitchens.

Recent evidence suggests that augmenting modern antihypertensive drugs with foods rich in p-coumaric acid, a naturally occurring phenolic acid, may offer a novel and effective strategy for blood pressure control.

Phenolic compounds, commonly found in fruits, vegetables, whole grains, and legumes, are known for their antioxidant, anti-inflammatory, and blood vessel–protective properties.

In a study, researchers investigated the combined effects of lisinopril, a widely used antihypertensive drugs and p-coumaric acid on hypertension.

They reported in the Comparative Clinical Pathology that p-coumaric acid enhance the antihypertensive action of lisinopril, potentially allowing for improved blood pressure control without increasing drug dosage.

The study used an established animal model in which hypertension was induced in rats through oral administration of L-NAME, a compound known to suppress nitric oxide production and raise blood pressure.

Following the induction of hypertension, the animals were treated for 14 days with p-coumaric acid (at two different doses), lisinopril alone, or a combination of both.

Untreated hypertensive rats showed significantly elevated activities of key enzymes linked to high blood pressure such as ACE, arginase, acetylcholinesterase, and phosphodiesterase-5 along with increased lipid peroxidation, an indicator of oxidative stress. At the same time, levels of nitric oxide, a critical molecule for blood vessel relaxation, were markedly reduced.

By contrast, rats treated with a combination of lisinopril and p-coumaric acid experienced notable improvements. Blood pressure was better controlled; harmful enzyme activities were reduced, oxidative stress declined, and nitric oxide levels increased. These improvements were mirrored in the tissues the heart compared with untreated hypertensive animals.

They said that the findings suggest that p-coumaric acid may enhance the antihypertensive action of lisinopril, potentially allowing for improved blood pressure control without increasing drug dosage.

This drug–food interaction model is particularly important in the circumstance of long-term hypertension management. Many patients rely on lifelong medication, and strategies that can improve treatment outcomes while reducing side effects are highly desirable.

The study also reinforces the growing recognition that diet is not merely supportive but can be biologically active in disease control.

The use of medicinal plants and plant-based therapies in the management of hypertension is deeply rooted in traditional medicine across many cultures. While such practices have often existed outside conventional healthcare systems, modern scientific research is now providing evidence-based explanations for their effectiveness.

While these findings are based on animal studies and cannot yet be directly translated into clinical recommendations for humans, they open the door to future research on dietary strategies that can safely complement antihypertensive drugs.

Further clinical studies are needed to determine appropriate dosages, safety profiles, and real-world effectiveness.

In the fight against hypertension, the future may lie not only in new drugs, but also in smarter combinations, where medicine and nutrition work together to deliver better, safer outcomes for patients.

Such nutrition to help maintain healthy blood pressure includes garlic, potatoes, walnuts,tomato and tomato products, legumes and citrus fruits (grapefruits and oranges).
(TRIBUNE)

News

Migration Agency Warns Migrants Against Irregular Travel Routes

Published

4 hours ago

May 28, 2026

Editor

The International Organisation for Migration (IOM), in collaboration with Giving is Healing Foundation, has sensitised residents of Ayobo in Alimosho Local Government Area of Lagos State on the dangers of irregular migration and the need to embrace legal travel procedures.

Speaking during a sensitisation programme held at Megida Ifelodu Community Development Association in Ayobo, the founder of Giving is Healing Foundation, Mr. Gbolahan Ayediran, warned intending migrants against using illegal travel routes.

Ayediran said many Nigerians desire to migrate abroad in search of better opportunities but often ignore proper procedures, thereby exposing themselves to several dangers.

“Lots of people want to migrate and most of them do it in the wrong direction. The reason for the programme is for us to advise people on how they can migrate in the right way. As much as migration is their right, they should do it correctly,” he said.

He advised intending travellers to obtain the necessary travel documents before embarking on any journey, noting that such documents include international passports, visas, flight tickets and yellow cards, depending on the destination country.

According to him, migrants should also gather adequate information about their destination countries to enable them make informed decisions before travelling.

Ayediran further highlighted some of the dangers associated with irregular migration, including abuse, exploitation, discrimination and forced labour.

Also speaking, the Chairman of Megida Ifelodu Community Development Association, Elder Mathews Amusan, commended the organisers for enlightening members of the community on safe migration practices.

He urged residents planning to travel abroad to always follow legal migration procedures to avoid falling victim to human trafficking and other migration-related challenges.

One of the participants, Mr. Kolawole Adenoko, said the programme enlightened him on the dangers of irregular migration and the importance of travelling through the proper channels.

He added that he would also educate his relatives and friends on the risks associated with illegal migration.

News

Shatta Wale Bailed Burna Boy From Ghana Prison After Arrest For Smoking Weed – Captan

Published

6 hours ago

May 28, 2026

Editor

Ghanian singer, Captan, has claimed that his former record label boss, Shatta Wale, once bailed Nigerian singer Burna Boy out of prison in Ghana after he was allegedly arrested for smoking weed.

Speaking in a recent podcast interview, Captan claimed that Shatta Wale sent him and others to free Burna Boy from police custody.

He also claimed that Shatta Wale and his group once accommodated Burna Boy when he was being hunted by some dangerous men.

Captan said, “I once bailed Burna Boy out of prison in Ghana when he was arrested for smoking weed. Shatta Wale sent me and some guys to go and free him from police custody.

“There was a time we also accommodated him when some people were after his life. We helped him settle the case.”

He added that he and Burna Boy are no longer in good terms after the Nigerian artist’s fallout with his mentor, Shatta Wale.

He, however, said he and Shatta Wale are open to reconciling with Burna Boy if he asks for it.

Watch the video here

News

Children’s Day: Chaos At Ogbe Stadium As Dozens Faint

Published

22 hours ago

May 27, 2026

Editor

Chaos erupted on Wednesday during the Children’s Day celebration as dozens of students reportedly collapsed following a stampede triggered by the use of pepper spray.

The event,
organised by the Edo State Ministry of Education at the Samuel Ogbemudia Stadium was disrupted after some male students of Ihogbe College allegedly made uncompromising advances towards female students at the venue.
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‎ A parent who identified himself as Oboh Emmanuel said, “the behaviour of those uncultured students attracted the attention of bouncers stationed at the stadium as they rebuked the male students.”
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‎Oboh said the affected students later regrouped and attacked the bouncers, leading to a confrontation within the crowded arena.

READ ALSO:Children’s Day: Edo Commits To Child Protection
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It was gathered that in the ensuing confusion, the bouncers were reported to have deployed pepper spray in an area occupied by a large number of students.
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‎Several students, particularly female students, reportedly fainted after inhaling the substance, while others sustained injuries after being stepped on during the ensuing melee.
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‎The panic was said to have spread across the stadium as students, teachers and parents scampered for safety.
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‎Many of the affected students were reportedly rushed to the Edo Specialist Hospital for medical attention.

Reacting to the incident, Chief Press Secretary to Governor Monday Okpebholo, Dr Patrick Ebojele, said the security personnel that fired the tear gas had been detained.

He said all the students, except two, that were rushed to the hospital have been discharged.

Ebojele stated that doctors wanted to observe the students till tomorrow before allowing them to go home.

“The two students are not seriously injured. Doctors want to observe them overnight. Permanent Secretary, Ministry of Education is still at the hospital. The man who used pepper spray has been detained.

“The incident did not happen the way it is being exaggerated. All modalities were put in place to ensure the children enjoyed their day.”
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