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The End Of Infertility? Skin Cells Used To Create Fertilizable Human Eggs

Published

8 months ago

October 1, 2025

Scientists said Tuesday they have turned human skin cells into eggs and fertilised them with sperm in the lab for the first time — a breakthrough that is hoped to one day let infertile people have children.

The technology is still years away from potentially becoming available to aspiring parents, the US-led team of scientists warned.

But outside experts said the proof-of-concept research could eventually change the meaning of infertility, which affects one in six people worldwide.

If successful, the technology called in-vitro gametogenesis (IVG) would allow older women or women who lack eggs for other reasons to genetically reproduce, Paula Amato, the co-author of a new study announcing the achievement, told AFP.

“It also would allow same-sex couples to have a child genetically related to both partners,” said Amato, a researcher at the Oregon Health & Science University in the United States.

Scientists have been making significant advances in this field in recent years, with Japanese researchers announcing in July they had created mice with two biological fathers.

But the new study, published in the journal Nature Communications, marks a major advance by using DNA from humans, rather than mice.

The scientists first removed the nucleus from normal skin cells and transferred them into a donor egg which had its nucleus removed. This technique, called somatic cell nuclear transfer, was used to clone Dolly the sheep in 1996.

However a problem still had to be overcome: skin cells have 46 chromosomes, but eggs have 23.

The scientists managed to remove these extra chromosomes using a process they are calling “mitomeiosis”, which mimics how cells normally divide.

They created 82 developing eggs called oocytes, which were then fertilised by sperm via in vitro fertilisation (IVF).

After six days, less than nine percent of the embryos developed to the point that they could hypothetically be transferred to the uterus for a standard IVF process.

However the embryos displayed a range of abnormalities, and the experiment was ended.

While the nine-percent rate was low, the researchers noted that during natural reproduction only around a third of embryos make it to the IVF-ready “blastocyst” stage.

Amato estimated the technology was at least a decade away from becoming widely available.

“The biggest hurdle is trying to achieve genetically normal eggs with the correct number and complement of chromosomes,” she said.

Breakthrough

Ying Cheong, a reproductive medicine researcher at the UK’s University of Southampton, hailed the “exciting” breakthrough.

“For the first time, scientists have shown that DNA from ordinary body cells can be placed into an egg, activated, and made to halve its chromosomes, mimicking the special steps that normally create eggs and sperm,” she said.

“While this is still very early laboratory work, in the future it could transform how we understand infertility and miscarriage, and perhaps one day open the door to creating egg- or sperm-like cells for those who have no other options.”

Other researchers trying to create eggs in the lab are using a different technique. It involves reprogramming skin cells into what are called induced pluripotent stem cells — which have the potential to develop into any cell in the body — then turning those into eggs.

“It’s too early to tell which method will be more successful,” Amato said. “Either way, we are still many years away.”
The researchers followed existing US ethical guidelines regulating the use of embryos, the study said.
(GUARDIAN)

News

Children’s Day: Chaos At Ogbe Stadium As Dozens Faint

Published

14 hours ago

May 27, 2026

Editor

Chaos erupted on Wednesday during the Children’s Day celebration as dozens of students reportedly collapsed following a stampede triggered by the use of pepper spray.

The event,
organised by the Edo State Ministry of Education at the Samuel Ogbemudia Stadium was disrupted after some male students of Ihogbe College allegedly made uncompromising advances towards female students at the venue.
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‎ A parent who identified himself as Oboh Emmanuel said, “the behaviour of those uncultured students attracted the attention of bouncers stationed at the stadium as they rebuked the male students.”
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‎Oboh said the affected students later regrouped and attacked the bouncers, leading to a confrontation within the crowded arena.

READ ALSO:Children’s Day: Edo Commits To Child Protection
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It was gathered that in the ensuing confusion, the bouncers were reported to have deployed pepper spray in an area occupied by a large number of students.
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‎Several students, particularly female students, reportedly fainted after inhaling the substance, while others sustained injuries after being stepped on during the ensuing melee.
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‎The panic was said to have spread across the stadium as students, teachers and parents scampered for safety.
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‎Many of the affected students were reportedly rushed to the Edo Specialist Hospital for medical attention.

Reacting to the incident, Chief Press Secretary to Governor Monday Okpebholo, Dr Patrick Ebojele, said the security personnel that fired the tear gas had been detained.

He said all the students, except two, that were rushed to the hospital have been discharged.

Ebojele stated that doctors wanted to observe the students till tomorrow before allowing them to go home.

“The two students are not seriously injured. Doctors want to observe them overnight. Permanent Secretary, Ministry of Education is still at the hospital. The man who used pepper spray has been detained.

“The incident did not happen the way it is being exaggerated. All modalities were put in place to ensure the children enjoyed their day.”
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News

Okpebholo Salutes Edo Muslims, Seeks Continued Support, Prayers

Published

15 hours ago

May 27, 2026

Editor

Governor Monday Okpebholo of Edo State has urged Muslims and all Nigerians to continue to pray for peace, unity and progress in the country even as they celebrate the annual Eid-al-Adha

The governor, who was represented by his deputy, Dennis Idahosa, stated this during the annual Eid-al-Adha celebration with Muslim faithfuls held at Government House in Benin City.

He reiterated his administration’s commitment to fairness, inclusivity and equal opportunities for all citizens irrespective of religion and tribe.

According to him, the present administration remains determined to building a government that reflects the diversity of Edo State, noting that competent and qualified Muslims have continued to play vital roles in his government because of their capacity, integrity and commitment to service.

“As a government, we remain committed to fairness, inclusivity and equal opportunity for every Edo citizen, irrespective of religion, ethnicity or political affiliation. This is why quality and competent Muslims are serving in key positions in our administration.”

Okpebholo appreciated the Muslim community in Edo State for their unwavering support and continuous prayers for his administration, noting that such prayers and support have contributed immensely to the peace and steady development being witnessed across the state.

He then called on all Nigerians to use the occasion of Eid-al-Adha to pray for the administration of President Bola Ahmed Tinubu, stressing that the country needs collective prayers, unity and cooperation to overcome its present economic and security challenges.

“I urge all Muslims and indeed all Nigerians to use this occasion to pray for our dear nation and for the administration of President Bola Ahmed Tinubu. Nigeria needs our collective prayers, unity and support as we strive to overcome our challenges and build a more prosperous future for all.”

In his remarks, the Chief Imam of Edo State, Abdulfatai Enabulele, applauded the governor for what he described as remarkable developmental strides recorded in less than two years in office.

The cleric commended the administration for ongoing infrastructural development and efforts geared towards improving governance in the state, but appealed to the government to revisit and complete some abandoned projects inherited from the previous administration for the benefit of the people.

News

Children’s Day: Edo Commits To Child Protection

Published

15 hours ago

May 27, 2026

Editor

The Edo State Government has reaffirmed its commitment to protecting the rights of children, promoting quality education, and strengthening sports development across the state.

This assurance was given by the governor of Edo State, Monday Okpebholo, during the 2026 Children’s Day Celebration and Governor’s Cup Finale held on Wednesday at the Samuel Ogbemudia Stadium, Benin City.

Addressing pupils, students and teachers,
the governor described children as the pride of Edo State and the future of the nation.

The governor, represented by his deputy, Dennis Idahosa,
noted that the annual celebration provides an opportunity to honour their dreams, talents, and limitless potential.

Speaking on this year’s Children’s Day theme, “Choose Kindness, Reject Bullying,” the governor said the message was timely and significant, as it emphasizes the need to create safe, supportive, and inclusive environments for children both in schools and communities.

He stated that bullying in all forms — physical, verbal, emotional, or online — has no place in society, adding that the Edo State Government remains fully committed to protecting the rights and dignity of every child.

According to him, the administration will continue to strengthen policies and programmes that promote child protection, discipline, mutual respect, and positive learning environments across schools in the State.

The governor urged children to embrace kindness, compassion, teamwork, and respect for one another, stressing that true strength lies not in intimidation but in empathy, good character, and mutual understanding.