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Nigeria Becomes First Country To Introduce New 5-in-1 Vaccine Against Meningitis – WHO

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Nigeria has become the first country in the world to roll out a new vaccine – Men5CV – recommended by the World Health Organization (WHO), to protect people against meningitis.

The World Health body, in a statement on Friday, said that the vaccine would protect people against five strains of Meningococcus bacteria and described Nigeria’s feat as historic.

It said that health workers would begin an immunisation campaign aimed at reaching one million people.

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The statement said that the vaccine and emergency vaccination activities are funded by Gavi, the Vaccine Alliance, which funds the global meningitis vaccine stockpile and supports lower-income countries with routine vaccination against meningitis.

According to the WHO, Nigeria is one of the 26 meningitis hyper-endemic countries in Africa, situated in the area known as the African Meningitis Belt.

It noted that in 2023, there was a 50 per cent jump in annual meningitis cases reported across Africa.

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“In Nigeria, an outbreak of Neisseria meningitidis (meningococcus) serogroup C outbreak, led to 1,742 suspected meningitis cases, including 101 confirmed cases and 153 deaths in seven of the 36 Nigerian states between October 2023 and March 2024.

“The states are Adamawa, Bauchi, Gombe, Jigawa, Katsina, Yobe, and Zamfara.

“To quell the deadly outbreak, a vaccination campaign was undertaken on March 25–28, 2024, to initially reach more than one million people aged 1-29 years,” it said.

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READ ALSO: HPV Vaccine: UNICEF Targets 400,000 Girls In Bauchi

The statement noted that meningitis is a serious infection that leads to the inflammation of the membranes (meninges) that surround and protect the brain and spinal cord.

“There are multiple causes of meningitis, including viral, bacterial, fungal, and parasitic pathogens.

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“Symptoms often include headache, fever, and stiff neck. Bacterial meningitis is the most serious and can also result in septicaemia (blood poisoning). It can seriously disable or kill within 24 hours,” the statement added.

It quoted Dr Tedros Ghebreyesus, WHO Director-General, as saying that meningitis was an old and deadly foe, adding that the new vaccine holds the potential to change the trajectory of the disease, preventing future outbreaks and saving many lives.

“Nigeria’s rollout brings us one step closer to our goal of eliminating meningitis by 2030,” Ghebreyesus said.

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He said that the revolutionary new vaccine offers a powerful shield against the five major strains of the meningococcal bacteria – A, C, W, Y, and X – in a single shot.

All five strains cause meningitis and blood poisoning.

According to him, this provides broader protection than the current vaccine used in much of Africa, which is only effective against the A strain.

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He said that the new vaccine has the potential to significantly reduce meningitis cases and advance progress in defeating meningitis.

“This is especially important for countries like Nigeria, where multiple serogroups are prevalent.

READ ALSO: Cervical Cancer: FG, UNICEF Flag Off Vaccination Of 48,000 Girls In Bauchi State

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“The new vaccine uses the same technology as the meningitis A conjugate vaccine (MenAfriVac®), which wiped out meningococcal A epidemics in Nigeria,” the WHO boss said.

The statement quoted Prof. Muhammad Pate, Nigeria’s Minister of Health and Social Welfare, as saying that Northern Nigeria, particularly the states of Jigawa, Bauchi, and Yobe, were badly hit by the deadly outbreak of meningitis.

“This vaccine provides health workers with a new tool to both stop this outbreak and also put the country on a path to elimination,” Pate said.

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According to him, Nigeria has done a lot of work preparing health workers and the health system for the rollout of the new vaccine.

“We got invaluable support from our populations in spite of the fasting period, and from our community leaders, especially the Emir of Gumel in Jigawa, who personally launched the vaccination campaign in the state.

“We’ll be monitoring progress closely and hopefully expand the immunisation in the coming months and years to accelerate progress,” he said.

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The minister said that the new multivalent conjugate vaccine took 13 years of effort and was based on a partnership between PATH and the Serum Institute of India.

“Financing from the UK government’s Foreign, Commonwealth, and Development Office was critical to its development,” he said.

Pate said that in July 2023, WHO prequalified the new Men5CV vaccine (which has brand name MenFive®), and in October 2023, it issued an official recommendation to countries to introduce the new vaccine.

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According to him, Gavi allocated resources for the Men5CV rollout in December 2023, which are currently available for outbreak response through the emergency stockpile managed by the International Coordinating Group (ICG) on vaccine provision.

READ ALSO: NAFDAC Gives Provisional Approval For R21 Malaria Vaccine

He added that the rollout, through mass preventive campaigns, was expected to start in 2025 across countries of the Meningitis Belt.

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Mr Andrew Mitchell, UK Minister for Development and Africa, was also quoted as saying that the rollout of one million vaccines in northern Nigeria would help save lives, prevent long-term illness, and boost the goal of defeating meningitis globally by 2030.

This is exactly the kind of scientific innovation supported by the UK, which I hope is replicated in years to come, to help us drive further breakthroughs, including wiping out other diseases,” Mitchell said.

He said that WHO has been supporting the Nigeria Centre for Disease Control and Prevention (NCDC) in responding to the meningitis outbreak in the country.

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According to him, the areas of support include disease surveillance, active case finding, sample testing, and case management.

“WHO and partners have also played a vital role in supporting Nigeria to prepare for the rollout of the new vaccine and training health workers,” he said.

Dr Nanthalile Mugala, PATH’s Chief of Africa Region, was also quoted as saying that meningococcal meningitis had tormented countries across Africa year after year.

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“The introduction of MenFive® in Nigeria heralds a transformative era in the fight against meningococcal meningitis in Africa.

“Building on the legacy of previous vaccination efforts, this milestone reflects over a decade of unwavering, innovative partnerships.

“The promise of MenFive® lies not just in its immediate impact but in the countless lives it stands to protect in the years to come, moving us closer to a future free from the threat of this disease,” Mugala said.

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READ ALSO: WHO To Establish TB Vaccine Accelerator Council

According to her, in 2019, WHO and partners launched the global roadmap to defeating meningitis by 2030.

“The roadmap sets a comprehensive vision towards a world free of meningitis and has three goals, including the elimination of bacterial meningitis epidemics.”

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Another goal is the reduction of cases of vaccine-preventable bacterial meningitis by 50 per cent and deaths by 70 per cent, as well as the reduction of disability and improvement of quality of life after meningitis, due to any cause.

Ms Aurélia Nguyen, Chief Programme Officer at Gavi, the Vaccine Alliance, was also quoted as saying that with outbreaks of infectious diseases on the rise worldwide, new innovations such as MenFive® were critical in helping the fight back.

She said that Vaccine Alliance funds the global stockpile as well as vaccine rollout in lower-income countries.

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“This first shipment signals the start of Gavi support for a multivalent meningococcal conjugate vaccine (MMCV) programme which, with the required donor funding for our next five years of work, will see pentavalent meningococcal conjugate vaccines rolled out in high-risk countries.

“Thanks to vaccines, we have eliminated large and disruptive outbreaks of meningitis A in Africa, and now we have a tool to respond to other serogroups that still cause large outbreaks, resulting in long-term disability and deaths,” Nguyen said.

According to her, following Nigeria’s meningitis vaccine campaign, a major milestone on the road to defeat meningitis is the international summit on meningitis taking place in Paris in April 2024, where leaders will celebrate progress, identify challenges and assess next steps.

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“It is also an opportunity for country leaders and key partners to commit, politically and financially, to accelerate progress towards eliminating meningitis as a public health problem by 2030,” she said. (NAN)
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South Korea, Japan Protest China, Russia Aircraft Incursions

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South Korea and Japan reacted furiously on Wednesday after Chinese and Russian military aircraft conducted joint patrols around the two countries, with both Seoul and Tokyo scrambling jets.

South Korea said it had protested with representatives of China and Russia, while Japan said it had conveyed its “serious concerns” over national security.

According to Tokyo, two Russian Tu-95 nuclear-capable bombers on Tuesday flew from the Sea of Japan to rendezvous with two Chinese H-6 bombers in the East China Sea, then conducted a joint flight around the country.

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The incident comes as Japan is locked in a dispute with China over comments Prime Minister Sanae Takaichi made about Taiwan.

READ ALSO:China Backs Nigeria, Warns Against Foreign Interference

The bombers’ joint flights were “clearly intended as a show of force against our nation, Defence Minister Shinjiro Koizumi wrote on X Wednesday.

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Top government spokesman Minoru Kihara said that Tokyo had “conveyed to both China and Russia our serious concerns over our national security through diplomatic channels”.

Seoul said Tuesday the Russian and Chinese warplanes entered its air defence zone and that a complaint had been lodged with the defence attaches of both countries in the South Korean capital.

Our military will continue to respond actively to the activities of neighbouring countries’ aircraft within the KADIZ in compliance with international law,” said Lee Kwang-suk, director general of the International Policy Bureau at Seoul’s defence ministry, referring to the Korea Air Defence Identification Zone.

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South Korea also said it deployed “fighter jets to take tactical measures in preparation for any contingencies” in response to the Chinese and Russian incursion into the KADIZ.

The planes were spotted before they entered the air defence identification zone, defined as a broader area in which countries police aircraft for security reasons but which does not constitute their airspace.

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Japan’s defence ministry also scrambled fighter jets to intercept the warplanes.

Beijing later Tuesday confirmed it had organised drills with Russia’s military according to “annual cooperation plans”.

READ ALSO:South Korean Actress Kim Sae-ron Found Dead In Seoul Apartment

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Moscow also described it as a routine exercise, saying it lasted eight hours and that some foreign fighter jets followed the Russian and Chinese aircraft.

Since 2019, China and Russia have regularly flown military aircraft into South Korea’s air defence zone without prior notice, citing joint exercises.

In November last year, Seoul scrambled jets as five Chinese and six Russian military planes flew through its air defence zone.

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Similar incidents occurred in June and December 2023, and in May and November 2022.

READ ALSO:Russia Insists Ukraine Must Cede Land Or Face Continued Military Push

Meanwhile, Tokyo said Monday it had scrambled jets in response to repeated takeoff and landing exercises involving fighter jets and military helicopters from China’s Liaoning aircraft carrier as it cruised in international waters near Japan.

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It also summoned Beijing’s ambassador after military aircraft from the Liaoning locked radar onto Japanese jets, the latest incident in the row ignited by Takaichi’s comments backing Taiwan.

Takaichi suggested last month that Japan would intervene militarily in any Chinese attack on the self-ruled island, which Beijing claims as its own and has not ruled out seizing by force.

AFP

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Thousands Reported To Have Fled DR Congo Fighting As M23 Closes On Key City

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Fierce fighting rocked the eastern Democratic Republic of Congo on Tuesday as the Rwanda-backed M23 militia rapidly advanced towards the strategic city of Uvira, with tens of thousands of people fleeing over the nearby border into Burundi, sources said.

The armed group and its Rwandan allies were just a few kilometres (miles) north of Uvira, security and military sources told AFP.

The renewed violence undermined a peace agreement brokered by US President Donald Trump that Kinshasa and Kigali signed less than a week ago, on December 4.

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Trump had boasted that the Rwanda-DRC conflict was one of eight he has ended since returning to power in America in January.

READ ALSO:Ambassadorial Nominees: Ndume Asks Tinubu To Withdraw List

With the new fighting, more than 30,000 people have fled the area around Uvira for Burundi in the space of a week, a UN source and a Burundian administrative source told AFP.

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The Burundian source told AFP on condition of anonymity he had recorded more than 8,000 daily arrivals over the past two days, and 30,000 arrivals in one week. A source in the UN refugee agency confirmed the figure.

The Rwanda-backed M23 offensive comes nearly a year after the group seized control of Goma and Bukavu, the two largest cities in eastern DRC, a strategic region rich in natural resources and plagued by conflict for 30 years.

Local people described a state of growing panic as bombardments struck the hills above Uvira, a city of several hundred thousand residents.

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Three bombs have just exploded in the hills. It’s every man for himself,” said one resident reached by telephone.

READ ALSO:South Africa Beat DR Congo In shootout To Finish Third At AFCON

We are all under the beds in Uvira — that’s the reality,” another resident said, while a representative of civil society who would not give their name described fighting on the city’s outskirts.

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Fighting was also reported in Runingo, another small locality some 20 kilometres (12 miles) from Uvira, as the M23 and the Rwandan army closed in.

Burundi views the prospect of Uvira falling to Rwanda-backed forces as an existential threat, given that it sits across Lake Tanganyika from Burundi’s economic capital Bujumbura.

The city is the main sizeable locality in the area yet to fall to the M23 and its capture would essentially cut off the zone from DRC control.

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READ ALSO:Stampede Kills 37 During Army Recruitment In Congo Capital

Burundi deployed about 10,000 soldiers to eastern DRC in October 2023 as part of a military cooperation agreement, and security sources say reinforcements have since taken that presence to around 18,000 men.

The M23 and Rwandan forces launched their Uvira offensive on December 1.

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Rich in natural resources, eastern DRC has been choked by successive conflicts for around three decades.

Violence in the region intensified early this year when M23 fighters seized the key eastern city of Goma in January, followed by Bukavu, capital of South Kivu province, a few weeks later.

– Regional risk –

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The peace deal meant to quell the fighting was signed last Thursday in Washington by Congolese President Felix Tshisekedi and his Rwandan counterpart Paul Kagame, with Trump — who called it a “miracle” deal — also putting his signature to it.

READ ALSO:FULL LIST: US To Review Green Cards From 19 ‘Countries Of Concern’ After Washington Shooting

The agreement includes an economic component intended to secure US supplies of critical minerals present in the region, as America seeks to challenge China’s dominance in the sector.

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But even on the day of the signing, intense fighting took place in South Kivu, where Uvira is located, which included the bombing of houses and schools.

Witnesses and military sources in Uvira said that Congolese soldiers fleeing the fighting had arrived in the city overnight Monday and shops were looted at dawn.

Several hundred Congolese and Burundian soldiers had already fled to Burundi on Monday, according to military sources, since the M23 fighters embarked on their latest offensive from Kamanyola, some 70 kilometres north of Uvira.
Since the M23’s lightning offensive early this year, the front had largely stabilised over the past nine months.

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Burundian President Evariste Ndayishimiye warned in February there was a danger of the conflict escalating into a broader regional war, a fear echoed by the United Nations.

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‘Santa Claus’ Arrested For Possessing, Distributing Child Sexual Abuse Material

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A 64-year-old man from Hamilton Township has been arrested in the United States after investigators linked him to the possession and distribution of child sexual abuse material.

The suspect, identified as Mark Paulino, had been working as a “Santa for hire” at holiday events, a role that placed him in repeated contact with children.

Mercer County officials said the investigation began on 4 December when detectives were alerted to suspicious online activity involving the uploading of child pornography from a residence in Hamilton Township. The probe quickly identified Paulino, a retired elementary school teacher, as the person involved.

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READ ALSO:Nigerian Ringleader Of Nationwide Bank Fraud, Money Laundering Jailed In US, Says FBI

Police stated that Paulino had presented himself online as a retired teacher and had recently performed as Santa Claus for photographs and private, corporate, and organisational events. “Because this role involved direct, repeated contact with children, detectives worked around the clock to secure a search warrant,” authorities explained.

The warrant was executed on 5 December, during which police seized multiple items regarded as evidentiary. Paulino was taken into custody without incident and charged with possession and distribution of child sexual abuse materials, as well as endangering the welfare of a child.

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Prosecutors have filed a motion to detain him pending trial. The investigation remains ongoing, and authorities have urged members of the public with relevant information to come forward.

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