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Nigeria Becomes First Country To Introduce New 5-in-1 Vaccine Against Meningitis – WHO

Published

2 weeks ago

April 13, 2024

Nigeria has become the first country in the world to roll out a new vaccine – Men5CV – recommended by the World Health Organization (WHO), to protect people against meningitis.

The World Health body, in a statement on Friday, said that the vaccine would protect people against five strains of Meningococcus bacteria and described Nigeria’s feat as historic.

It said that health workers would begin an immunisation campaign aimed at reaching one million people.

The statement said that the vaccine and emergency vaccination activities are funded by Gavi, the Vaccine Alliance, which funds the global meningitis vaccine stockpile and supports lower-income countries with routine vaccination against meningitis.

According to the WHO, Nigeria is one of the 26 meningitis hyper-endemic countries in Africa, situated in the area known as the African Meningitis Belt.

It noted that in 2023, there was a 50 per cent jump in annual meningitis cases reported across Africa.

“In Nigeria, an outbreak of Neisseria meningitidis (meningococcus) serogroup C outbreak, led to 1,742 suspected meningitis cases, including 101 confirmed cases and 153 deaths in seven of the 36 Nigerian states between October 2023 and March 2024.

“The states are Adamawa, Bauchi, Gombe, Jigawa, Katsina, Yobe, and Zamfara.

“To quell the deadly outbreak, a vaccination campaign was undertaken on March 25–28, 2024, to initially reach more than one million people aged 1-29 years,” it said.

The statement noted that meningitis is a serious infection that leads to the inflammation of the membranes (meninges) that surround and protect the brain and spinal cord.

“There are multiple causes of meningitis, including viral, bacterial, fungal, and parasitic pathogens.

“Symptoms often include headache, fever, and stiff neck. Bacterial meningitis is the most serious and can also result in septicaemia (blood poisoning). It can seriously disable or kill within 24 hours,” the statement added.

It quoted Dr Tedros Ghebreyesus, WHO Director-General, as saying that meningitis was an old and deadly foe, adding that the new vaccine holds the potential to change the trajectory of the disease, preventing future outbreaks and saving many lives.

“Nigeria’s rollout brings us one step closer to our goal of eliminating meningitis by 2030,” Ghebreyesus said.

He said that the revolutionary new vaccine offers a powerful shield against the five major strains of the meningococcal bacteria – A, C, W, Y, and X – in a single shot.

All five strains cause meningitis and blood poisoning.

According to him, this provides broader protection than the current vaccine used in much of Africa, which is only effective against the A strain.

He said that the new vaccine has the potential to significantly reduce meningitis cases and advance progress in defeating meningitis.

“This is especially important for countries like Nigeria, where multiple serogroups are prevalent.

“The new vaccine uses the same technology as the meningitis A conjugate vaccine (MenAfriVac®), which wiped out meningococcal A epidemics in Nigeria,” the WHO boss said.

The statement quoted Prof. Muhammad Pate, Nigeria’s Minister of Health and Social Welfare, as saying that Northern Nigeria, particularly the states of Jigawa, Bauchi, and Yobe, were badly hit by the deadly outbreak of meningitis.

“This vaccine provides health workers with a new tool to both stop this outbreak and also put the country on a path to elimination,” Pate said.

According to him, Nigeria has done a lot of work preparing health workers and the health system for the rollout of the new vaccine.

“We got invaluable support from our populations in spite of the fasting period, and from our community leaders, especially the Emir of Gumel in Jigawa, who personally launched the vaccination campaign in the state.

“We’ll be monitoring progress closely and hopefully expand the immunisation in the coming months and years to accelerate progress,” he said.

The minister said that the new multivalent conjugate vaccine took 13 years of effort and was based on a partnership between PATH and the Serum Institute of India.

“Financing from the UK government’s Foreign, Commonwealth, and Development Office was critical to its development,” he said.

Pate said that in July 2023, WHO prequalified the new Men5CV vaccine (which has brand name MenFive®), and in October 2023, it issued an official recommendation to countries to introduce the new vaccine.

According to him, Gavi allocated resources for the Men5CV rollout in December 2023, which are currently available for outbreak response through the emergency stockpile managed by the International Coordinating Group (ICG) on vaccine provision.

He added that the rollout, through mass preventive campaigns, was expected to start in 2025 across countries of the Meningitis Belt.

Mr Andrew Mitchell, UK Minister for Development and Africa, was also quoted as saying that the rollout of one million vaccines in northern Nigeria would help save lives, prevent long-term illness, and boost the goal of defeating meningitis globally by 2030.

“This is exactly the kind of scientific innovation supported by the UK, which I hope is replicated in years to come, to help us drive further breakthroughs, including wiping out other diseases,” Mitchell said.

He said that WHO has been supporting the Nigeria Centre for Disease Control and Prevention (NCDC) in responding to the meningitis outbreak in the country.

According to him, the areas of support include disease surveillance, active case finding, sample testing, and case management.

“WHO and partners have also played a vital role in supporting Nigeria to prepare for the rollout of the new vaccine and training health workers,” he said.

Dr Nanthalile Mugala, PATH’s Chief of Africa Region, was also quoted as saying that meningococcal meningitis had tormented countries across Africa year after year.

“The introduction of MenFive® in Nigeria heralds a transformative era in the fight against meningococcal meningitis in Africa.

“Building on the legacy of previous vaccination efforts, this milestone reflects over a decade of unwavering, innovative partnerships.

“The promise of MenFive® lies not just in its immediate impact but in the countless lives it stands to protect in the years to come, moving us closer to a future free from the threat of this disease,” Mugala said.

According to her, in 2019, WHO and partners launched the global roadmap to defeating meningitis by 2030.

“The roadmap sets a comprehensive vision towards a world free of meningitis and has three goals, including the elimination of bacterial meningitis epidemics.”

Another goal is the reduction of cases of vaccine-preventable bacterial meningitis by 50 per cent and deaths by 70 per cent, as well as the reduction of disability and improvement of quality of life after meningitis, due to any cause.

Ms Aurélia Nguyen, Chief Programme Officer at Gavi, the Vaccine Alliance, was also quoted as saying that with outbreaks of infectious diseases on the rise worldwide, new innovations such as MenFive® were critical in helping the fight back.

She said that Vaccine Alliance funds the global stockpile as well as vaccine rollout in lower-income countries.

“This first shipment signals the start of Gavi support for a multivalent meningococcal conjugate vaccine (MMCV) programme which, with the required donor funding for our next five years of work, will see pentavalent meningococcal conjugate vaccines rolled out in high-risk countries.

“Thanks to vaccines, we have eliminated large and disruptive outbreaks of meningitis A in Africa, and now we have a tool to respond to other serogroups that still cause large outbreaks, resulting in long-term disability and deaths,” Nguyen said.

According to her, following Nigeria’s meningitis vaccine campaign, a major milestone on the road to defeat meningitis is the international summit on meningitis taking place in Paris in April 2024, where leaders will celebrate progress, identify challenges and assess next steps.

“It is also an opportunity for country leaders and key partners to commit, politically and financially, to accelerate progress towards eliminating meningitis as a public health problem by 2030,” she said. (NAN)
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Pop Star Justin Bieber Sparks Concern After Seen Crying Amid Rumours Of Rift With Wife

Published

1 day ago

April 28, 2024

Editor

Pop sensation Justin Bieber has stirred concern among fans after posting a series of emotional selfies on Sunday, that has been linked to the rumoured split with his wife.

The 30-year-old singer took to Instagram over the weekend to share multiple photo dumps, offering glimpses into various aspects of his life.

From his surprise appearance at Coachella, where he performed during Tems’ set, to moments of leisure such as playing golf, enjoying the beach, smoking, and trying on different trainers, Justin Bieber’s posts provided a look into his world.

It was, however, one particular set of images that garnered significant attention from fans.

In a close-up series of selfies, Bieber appeared visibly distressed, with tears streaming down his face.

The pop star stared solemnly into the camera, his emotions laid bare for all to see, as a single tear rolled down his cheek.

Despite the intimate portrayal of his emotions, Bieber offered no explanation or caption for his tearful display, leaving fans puzzled and concerned about his well-being.

Justin Bieber’s personal life has come under the spotlight since the recent rumors surrounding his marriage to wife Hailey Bieber (neé Baldwin), 27.

The couple, who tied the knot in 2018, has faced speculation about the state of their relationship on multiple occasions.

Concerns were raised recently when Hailey’s father, Stephen Baldwin, 57, requested “prayers” for the couple, fueling speculation about potential marital troubles.

Headline

400 Bodies Found In Mass Grave In Gaza Hospital

Published

2 days ago

April 28, 2024

Editor

The government in Gaza have concluded their search of mass graves at a hospital in the south of the strip and said they have uncovered a total of 392 bodies, including some still wearing surgical gowns.

Speaking at a Thursday news conference at Rafah, on April 25, an official from the Palestinian Civil Defense in Gaza said workers have identified 165 bodies at the Nasser Medical Complex in Khan Younis, following the withdrawal of Israeli forces from the area earlier this month.

According to Mohammed Al Mighayyer, they are still examining the remaining 227 bodies to determine their identities.

“We found three mass graves, the first in front of the morgue, the second behind the morgue, and the third north of the dialysis building,” he added.

The Israel Defense Forces (IDF) said any suggestion that it had buried Palestinian bodies in mass graves was false, and that a grave at the Nasser complex was dug by Palestinians in Gaza some months ago.

The Gaza Civil Defense acknowledged that around 100 bodies were buried in graves at the Nasser hospital before the IDF operation there.

CNN reports that people had buried the bodies of family members who had been killed on the grounds of the hospital as a temporary measure in January but when they returned after the Israeli military withdrew on April 7, they discovered the bodies had been dug up and then placed in at least one collective grave, not all in the initial spots they were buried in.

The Palestinian Civil Defense also showed graphic images on a TV screen at the news conference showing several almost unrecognizable bodies at the complex and bodies of decomposed children.

Al Mighayyer said the Civil Defense “witnessed the presence of children’s bodies in the mass graves at the Nasser Medical Complex, which proves crimes of genocide.” While the group says it is still examining the bodies, they suspect at least 20 civilians were buried alive in the complex, but it did not explain how it knows this, or offer proof.

Al Mighayyer also claimed there had been cases of executions of patients who had been receiving treatment at the hospital. He said several bodies were found with gunshot wounds to their heads and injuries to their bodies.

Al Mighayyer said at the news conference that the Palestinian Gaza Civil Defense in Gaza “discovered torture marks on [some] bodies.” CNN cannot independently verify these claims.

“Israeli forces buried several bodies in plastic bags at a depth of three meters, which made them decompose quickly.”

“The occupation deliberately concealed evidence of its crimes in the Nasser Complex by changing the plastic shrouds more than once,” he claimed. Video recorded by CNN shows bodies wrapped in three different coloured shrouds: white, black and blue.

Amnesty International has also called for an investigation into the mass graves at the two Gaza hospitals.

I’m response, the Israeli Defense Forces, IDF said:“During the IDF’s operation in the area of Nasser Hospital, in accordance with the effort to locate hostages and missing persons, corpses buried by Palestinians in the area of Nasser Hospital were examined. The examination was conducted in a careful manner and exclusively in places where intelligence indicated the possible presence of hostages.”

The IDF continued: “At the end of February, IDF forces conducted a precise and targeted operation against the terrorist organization Hamas in the Nasser Hospital area. During the operation, about 200 terrorists who were in the hospital were apprehended, medicines intended for Israeli hostages were found undelivered and unused, and a great deal of ammunition was confiscated. The activity was done in a targeted manner and without harming the hospital, the patients and the medical staff.”

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Watch Of Richest Titanic Passenger Sells For £1.17m

Published

2 days ago

April 27, 2024

Editor

A gold watch found on the body of the richest passenger on the Titanic was auctioned in England for £1.17 million ($1.46 million) on Saturday.

It was a record sum for an object linked to the notorious 1912 shipping disaster, said auctioneers Henry Aldridge & Son.

A US buyer won the bidding war, smashing the auctioneer’s pre-sale estimate of between £100,000 and £150,000.

The watch, engraved with the initials JJA, belonged to the US business magnate John Jacob Astor.

Astor was 47 when he died as the Titanic sank in the early hours of April 15, 1912. He was reputed to be one of the richest men in the world at the time.

He died after having helped his wife, Madeleine, on board one of the lifeboats. She survived the disaster.

Astor’s body was found a week after the disaster, with the watch among his personal belongings.

“The watch itself was completely restored after being returned to Colonel Astor’s family and worn by his son,” said a statement from the auction house.