Health
See Drug That May Increase Lifespan By 30%
Published
2 years agoon
By
Editor
Researchers are studying how Rapamycin, a drug that has been used for the treatment of transplant rejections and various types of cancer, can also slow down cellular growth and division.
They have carried out studies in yeast, worms, and mice which have shown that the drug can increase lifespan by up to 30%. This is thought to be due to rapamycin’s capacity to slow down cellular aging and reduces the incidence of age-related diseases. They however, further research is needed to determine whether the drug has the same lifespan-extending effects in humans.
A type of macrolide antibiotic originally isolated from the soil bacteria Streptomyces hygroscopicus in the 1970s, indications are this drug was used as an antifungal agent, but its immunosuppressive properties were later discovered.
READ ALSO: UK Nurses Prepared To Strike Until Christmas
Rapamycin has a complex mechanism of action, targeting a protein called mTOR (mammalian target of rapamycin). mTOR is a vital protein involved in many cellular processes, including cell cycle regulation and protein synthesis.
By inhibiting mTOR, research shows that rapamycin slows down cellular growth and division, which is necessary to prevent the rejection of transplanted organs.
One way rapamycin inhibits mTOR is by binding to a protein called FKBP12. This complex then interacts with mTORC1 (mTOR complex 1), which inhibits the protein’s activity.
This then leads to a reduction in the synthesis of proteins needed for cell division and cell cycle progression. The drug also inhibits mTORC2 (mTOR complex 2), which is necessary for cell survival, migration, and metabolism.
Rapamycin has been particularly effective in treating several types of cancer, including renal cell carcinoma, breast cancer, and lymphoma. In these cancers, the drug slows down cancer cell growth and division, leading to the death of the cancer cells.
READ ALSO: Gunmen Shoot Ex-Indian Lawmaker, Brother Dead On Live TV
Additionally, rapamycin has been shown to improve the efficacy of chemotherapy drugs, making them more effective in killing cancer cells.
In conclusion, rapamycin is a drug with complex mechanism of action and has been found to be particularly effective in treating several types of cancer.
Further research is however needed to determine its potential lifespan-extending effects in humans.
However, rapamycin’s use in clinical practice is currently limited due to its side effects, which include an increased risk of infections, kidney damage, and diabetes.
You may like
FG To Disburse N25bn Healthcare Enhancement Funds To States
Don Confirms ‘Zobo’ As Antihypertensive Therapy
HEALTH CORNER: Indian Hemp Benefits, Risk In Its Consumption
HEALTH CORNER: What You Need Know About Chlamydia Infection, Prevention
HEALTH CORNER: Why You Should Not Hold Your Sneeze
Five Foods To Avoid In The Morning
Health
LASG FLags Off Polio Outbreak Response Campaign
Published
6 months agoon
January 20, 2025By
Editor
The Lagos State Government, through the Lagos State Primary Health Care Board, has launched the 2025 Polio Outbreak Response Campaign, reaffirming its commitment to eradicating polio and safeguarding the health of its children.
The ceremony, held at the Simpson Primary Healthcare Centre, was led by the First Lady of Lagos State, Dr. (Mrs.) Claudiana Ibijoke Sanwo-Olu, represented by Mrs. Widad Jumoke Mustafa, a member of the Committee of Wives of Lagos State Officials (COWLSO).
In her address, the First Lady emphasised the state government’s proactive measures to keep Lagos polio-free, highlighting the critical importance of the campaign in preventing the debilitating effects of poliomyelitis, which can result in paralysis or death.
READ ALSO: IMPEACHMENT: Lagos Ex-Speaker, Obasa’s ‘Sins’ Revealed
The First Lady also called on parents, community leaders, and stakeholders to support the campaign by ensuring eligible children are vaccinated.
Targeting children aged 0-59 months, vaccination teams will administer the Oral Polio Vaccine (OPV) to prevent virus transmission.
Dr. Kemi Ogunyemi, the Special Adviser on Health, expressed gratitude to Lagosians for their continued cooperation in the fight against polio. While appreciating all healthcare workers and partners for their services, Mrs. Ogunyemi encouraged parents to present their children and wards for the exercise.
Also speaking, the Chairman of Lagos Mainland Local Government, Mrs. Omolola Rashidat Essien opined that Immunization is key in ensuring that children are kept safe from polio and other vaccine preventable diseases.
Dr. Abimbola Bowale, the Supervising Permanent Secretary, Lagos State Primary Health Care Board, who also spoke at the event, underscored the life-saving importance of immunization.
“All children aged 0-59 months need multiple doses of the polio vaccine to ensure full protection. Any child missed represents a potential risk for the poliovirus to spread. The vaccine is safe, effective, and crucial in keeping our communities polio-free,” he stated.
Dr. Bowale also outlined several strategies to ensure the success of the campaign, including fixed post teams stationed at primary healthcare centres and public health facilities, house-to-house visits, and a transit strategy to reach special locations such as places of worship, schools, motor parks, and other public venues.
The event concluded with Dr. (Mrs.) Claudiana Ibijoke Sanwo-Olu officially launched the campaign, marking a renewed effort to maintain Lagos State’s polio-free status.

The Lagos state suspected cholera cases have risen to 421.
The Commissioner for Health, Akin Abayomi disclosed this on his Instagram handle @profakinabayomi on Saturday.
“As of June 20, 2024, an additional four suspected cholera cases have been reported, as illustrated in the accompanying graph,” he wrote.
He noted that the Emergency Operations Centre in collaboration with all relevant partners is actively engaged in contact tracing, community-based surveillance, awareness campaigns, sample testing, and ensuring that confirmed cholera cases receive appropriate medical treatment.
READ ALSO: Two Suspects Arrested For Stealing Car From Mosque During Juma’at Prayer
On Friday, the commissioner confirmed 35 cases out of the 417 suspected cases and 24 deaths across 20 Local Government Areas in the state.
The cases were reported from Agege, Badagry, Ikeja, Mushin, Ajeromi-Ifelofun, Epe, Ikorodu, Ojo, Alimosho, and Eti-Osa.
Others were Kosofe, Oshodi-Isolo, Amuwo-Odofin, Ibeju-Lekki, Lagos Island, Shomolu, Apapa, Ifako-Ijaiye, Lagos mainland, and Surulere.
Cholera is a food and water-borne disease caused by ingesting the bacteria— Vibrio cholerae — in contaminated water and food. Cholera can cause severe acute watery diarrhoea, and the severe forms of the disease can kill within hours if left untreated.
In Nigeria, cholera is an endemic and seasonal disease, occurring annually mostly during the rainy season and more frequently in areas with poor sanitation.
READ ALSO: Police Arrest 28yr Old Suspected Cultists, Recover Gun In Delta Community
The World Health Organisation on Thursday announced a spike in cholera in several regions of the world, with almost 195,000 cases and over 1,900 deaths reported in 24 countries since the start of 2024.
WHO said the Eastern Mediterranean Region reported the highest number of cases, followed by the African Region, the Region of the Americas, the Southeast Asia Region, and the European Region.
The global health body, however, noted that there are no reported cases in the Western Region, according to its bulletin released on Wednesday.
It said it exhausted its global stockpile of Oral Cholera Vaccines by March but was able to exceed “the emergency target of five million doses in early June for the first time in 2024.”

By Silver Yeibake
Autism, commonly known as Autism Spectrum Disorder (ASD), is a neurodevelopmental disorder that affects communication, social interaction, and behavior. Autism is referred to as a spectrum condition since it can manifest in a variety of symptoms and abilities. While the actual cause of autism is unknown, evidence suggests that genetic and environmental factors interact to influence its development.
The risk factors include a sibling with autism, advanced age of parents, exposure to certain air pollutants and pesticides before birth, extreme prematurity, mothers with diabetes, immune system disorders or obesity, any difficulty with delivery leading to deprivation of oxygen to the baby’s brain, fever during pregnancy, lack of certain vitamins minerals during pregnancy, and certain genetic conditions, such as Down, fragile X, and Rett syndromes.
“Risk factors can not on their own cause a disease. However, they can increase the likelihood of that disease in a person.”
It is important to know that contrary to trending claims online, there is no scientific or medical evidence that vaccines or consumption of sugar are risk factors for autism.
READ ALSO: Kidney Stones: What You Need To Know
Autism is defined by difficulties in social interaction and communication. Individuals with autism may struggle to grasp social cues, maintain eye contact, and engage in typical back-and-forth conversations. Some people may also engage in meaningless, repetitive actions, such as hand-flapping or rocking, and have strong interests in specific areas.
It is essential to remember that autism is a lifelong diagnosis, but with early intervention and adequate care, people with autism can live fulfilling lives.
Autism treatment frequently includes behavioral therapy, speech therapy, occupational therapy, and social skills training. Each individual with autism is unique, thus interventions should be tailored to meet their personal needs and strengths.
In spite of the difficulties that autism can cause, many people with autism possess unique talents and abilities. Some people may succeed in fields such as music, art, mathematics, or programming, thus it is important for society to acknowledge and honor the qualities and achievements of people with autism.
In summary, autism is a complicated and diverse disorder that affects individuals in various ways. By raising autism knowledge, understanding, and acceptance, we can build a more inclusive society in which people with autism can thrive and attain their full potential.
Dr. Yeibake, Weriwoyingipre Silver.
Senior Registrar,
Faculty Of Pediatrics,
WACP
- Congress Newspaper @4: X-Raying The Evolution Of Media In Ijaw Nation
- JUST IN: Psychiatric Hospital Staff Shot Dead In Benin
- Supreme Court: Jubilant Supporters Stunned, Locked Out Of Edo Govt House [PHOTOS]
- Gunmen Invade Catholic Seminary School In Edo, Kill One, Abduct Three
- Pastor Arraigned Over Alleged Rape Of Married Woman In Edo
- OPINION: BAT Rejects Trump’s Amazing Offer
- Nurses Reject NSIWC Circular On Allowances
- LASIEC Releases Validated Candidates’ List Gor Lagos LG Polls
- Lagos Police Deploys 30,000 Officers For LG Polls
- How Law Student’s Inability To Pay N120,000 Caused Her Death At UNIZIK
About Us
Trending
- Metro2 days ago
Mysterious Bird Found Inside Auchi Poly Lecturer’s Office, Killed
- News4 days ago
BREAKING: FG Officially Releases Age Limit For Admission Into Tertiary Institutions
- News4 days ago
OPINION: APC’s Leprosy Versus ADC’s Scabies
- Politics3 days ago
‘The Man I Defeated 32 Years Ago Hasn’t Forgiven Me’ – Ita-Giwa Laments Discrimination Against Women In Politics
- News5 days ago
Flash Flood Warning: Sokoto, Edo, Akwa Ibom, 17 Other States At Risk In July — NiMet
- Politics4 days ago
97 Lawyers Line Up To Defend ADC, Mark, Aregbesola Against APC’s ‘Fake Lawsuit’
- Entertainment5 days ago
OPINION: From The North, ‘A Storm Is Coming’
- News4 days ago
Obi In Benin, Donates N15m To St Philomena School of Nursing Sciences
- News2 days ago
‘I Feel Your Pain’ – Ighodalo Reacts To S’Court Verdict On Edo Guber Election
- Politics5 days ago
INEC Announces Dates For Commencement Of Continuous Voter Registration In Osun