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Second Pig Heart Transplant Recipient Dies Six Weeks After Procedure

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A 58-year-old man with terminal heart disease who received the world’s second genetically-modified pig heart transplant has died nearly six weeks after the procedure, the medical center that carried out the surgery said.

Lawrence Faucette received the organ on September 20 and passed away on October 30, the University of Maryland Medical Center said in a statement on Tuesday.

He had been deemed ineligible for a human heart transplant because of his advanced medical conditions, including peripheral vascular disease. Though the transplant initially worked well, it began showing signs of rejection in recent days.

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We mourn the loss of Mr. Faucette, a remarkable patient, scientist, Navy veteran, and family man who just wanted a little more time to spend with his loving wife, sons, and family,” said surgeon Bartley P. Griffith, who performed the transplant.

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The latest experimental procedure was part of a growing field of research aimed at advancing cross-species transplants, or xenotransplants, involving animal organs genetically modified to become less likely to trigger rejection in humans.

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It is hoped that eventually they will help address the human donor gap, with more than 100,000 people in America alone currently awaiting an organ.

David Bennett Sr was the first person to receive a gene-edited pig heart transplant in January 2022, carried out by the same medical team.

He passed away after two months with the medical center ascribing his death to “a multitude of factors including his poor state of health” prior to the operation, though it was also later found that the organ was infected with a virus.

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Muhammad Mohiuddin, the cardiac xenotransplantation program director, praised Faucette’s contribution to science, adding: “We intend to conduct an extensive analysis to identify factors that can be prevented in future transplants.”

Over the past two years, doctors have transplanted kidneys from genetically modified pigs into brain-dead patients.

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The NYU Langone Hospital Transplant Institute in New York announced in September that a pig kidney transplanted into a brain-dead patient had functioned for a record-breaking 61 days.

Early xenotransplantation research focused on harvesting organs from primates — for example, a baboon heart was transplanted into a newborn known as “Baby Fae” in 1984, but she survived only 20 days.

Current efforts focus on pigs, which are thought to be ideal donors for humans because of their organ size, their rapid growth and large litters, and the fact they are already raised as a food source.

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AFP

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Netanyahu Asks Israeli President For Pardon From Corruption Charges

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Israeli Prime Minister, Benjamin Netanyahu, has asked the country’s president for a pardon in his long-running corruption case, saying the criminal proceedings are hindering his ability to govern and that ending the trial would benefit the nation.

Netanyahu, Israel’s longest-serving prime minister, has denied the bribery, fraud and breach of trust charges.

His lawyers told the president’s office that he still believes the legal process will eventually lead to a complete acquittal.

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READ ALSO:Israeli PM Netanyahu Back In Court For Graft Trial

My lawyers sent a request for pardon to the president of the country today. I expect that anyone who wishes for the good of the country support this step,” Netanyahu said in a brief video statement released by his Likud party.

The prime minister, who has been on trial for five years, has not admitted guilt, and neither have his lawyers. Opposition leader Yair Lapid said Netanyahu should not receive a pardon unless he admits wrongdoing, expresses remorse and immediately withdraws from political life.

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Pardons in Israel are usually granted only after a conviction, but Netanyahu’s lawyers argued the president can step in when public interest is at stake, saying intervention could help heal national divisions and promote unity.

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President Isaac Herzog’s office described the request as “extraordinary” with “significant implications”. His office said the president “will responsibly and sincerely consider the request” after receiving the necessary opinions.

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United States President, Donald Trump, recently wrote to Herzog urging him to consider approving the pardon, describing the case against Netanyahu as “a political, unjustified prosecution”.

Herzog’s office said the request will be sent to the justice ministry’s pardons department to gather assessments that will be forwarded to the president’s legal adviser, who will prepare a recommendation.

(Reuters)

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US: Four Killed, 10 Others Wounded In California Shooting

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Four people were confirmed dead and 10 others injured after a shooting at a family gathering in California, United States on Saturday night, according to US police, who described the attack as a “targeted incident.”

The incident occurred inside a banquet hall in Stockton, northeast of San Francisco, shortly before 6:00 pm, spokesperson for the San Joaquin County Sheriff’s Office, Heather Brent, told reporters during a news briefing.

Brent said the victims, ranging from “juveniles to adults,” were rushed to nearby hospitals, noting that details about the shooting remained limited.

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READ ALSO:FULL LIST: US To Review Green Cards From 19 ‘Countries Of Concern’ After Washington Shooting

“What we have confirmed at this time is that there was a banquet hall where a family was celebrating. We have 14 victims of this shooting. Four of those are deceased,” Brent said.

“Early indications suggest that this may be a targeted incident. Investigators are exploring all possibilities at this time.”

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The sheriff’s office posted on social media that detectives were “working to determine the circumstances leading up to this tragedy.”

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“We are urging anyone with information, video footage, or who may have witnessed any part of this incident to contact the San Joaquin County Sheriff’s Office immediately,” the post added.

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Authorities said no suspect had been identified at the time of the report.

California Governor Gavin Newsom was briefed on the development, his office said in a social media statement.

Data from the Gun Violence Archive shows there have been 504 mass shootings in the United States so far this year, including the Stockton attack.

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(AFP)

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FULL LIST: US To Review Green Cards From 19 ‘Countries Of Concern’ After Washington Shooting

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The Trump administration announced on Thursday that it will review the immigration status of all permanent residents, or “Green Card” holders, from Afghanistan and 18 other countries following the attack on National Guard troops in Washington, D.C.

U.S. officials identified the suspect in Wednesday’s shooting as a 29-year-old Afghan national who previously worked alongside American forces in Afghanistan.

The individual was granted asylum earlier this year, not permanent residency, according to AfghanEvac, an organisation that assists Afghans resettled in the United States after the Taliban takeover in 2021.

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I have directed a full-scale, rigorous reexamination of every Green Card for every alien from every country of concern,” said Joseph Edlow, director of U.S. Citizenship and Immigration Services (USCIS), on X.

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The review follows a June executive order from President Trump classifying 19 countries as “of Identified Concern.”

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The order banned entry for nearly all nationals from 12 countries, including Afghanistan. The full list of these countries is:

Afghanistan

Myanmar

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Chad

Congo-Brazzaville

Equatorial Guinea

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Eritrea

Haiti

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Iran

Libya

Somalia

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Sudan

Yemen

A partial travel ban applies to seven additional countries, though some temporary work visas remain allowed: Burundi, Cuba, Laos, Sierra Leone, Togo, Turkmenistan, and Venezuela.

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